Hormonal contraceptives and systemic lupus erythematosus and rheumatoid arthritis
ESC Congress Library. Semedo Leite T. May 28, 2014; 50488; A-072
Dr. Tatiana Semedo Leite
Dr. Tatiana Semedo Leite
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Abstract
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Objective(s): Women with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) and their clinicians may have unique concerns about hormonal methods of contraception, however pregnancy can be particularly risky in women with active disease or on teratogenic medications making contraception an important issue for women, particularly in the case of SLE. Furthermore, we believe that knowledge of disease flares and the influence of hormonal contraception could have implications for counselling patients on prevention to control their disease if they are able to predict a flare, and though have impact on quality of life.


The aim of our study is to evaluate the influence of hormonal contraception in systemic lupus erythematosus and rheumatoid arthritis disease course and study self-reported flares related to the use of hormonal contraceptives and when not under them.


Design & Methods: This study was performed by evaluating the women's files attending the Autoimmune Diseases' medical appointment at Faro's hospital between January 2013 and December 2013. Additionally, these patients underwent a questionnaire pre-coded with an ID number to allow review of the data and confirmation of information provided by the patient when needed. Functional ability was assessed using the Health Assessment Questionnaire (HAQ).


Before its beginning, this study got the Ethics' Commission approval. Statistical analysis was performed using SPSS 18.0.


Results: at the time of the call for abstracts, data is still being collected, so there is a lack of definitive results. These results are being collected into 2 groups: those with SLE and those with RA. Data collected, beyond women's demographic characteristics,is including information about the onset of disease and its relation with hormonal contraception, regularity and evolution of menstrual cycle and related flares with and without hormonal contraceptive methods. Signs of disease severity were taken in account.


Conclusions: Because results are still being collected and soon will be under statistical analysis, we do not have still definitive conclusions. However, we speculate from studying these patients in clinic that there were not more complains or adverse outcomes when using these contraceptive methods in selected cases. In what concerns specifically to RA, and in accordance to previous studies, hormonal contraception seems to have beneficial outcomes.

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