EFFICACY AND TOLERANCE OF EMERGENCY CONTRACEPTION WITH LEVONORGESTREL IN A DOSE OF 1,5 mg (ESCAPELLE).
ESC Congress Library. Dovletkhanova E. 05/28/14; 50544; A-129
Dr. Elmira Dovletkhanova
Dr. Elmira Dovletkhanova
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Abstract
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Objectives: to assess efficacy and tolerance of levonorgestrel-containing contraceptive Escapelle in women for emergency contraception


Materials and Methods: We investigated 35 women, aged from 18 to 39 (mean age 23.4+/-1.1) coming to the Centre for emergency contraception. All women visited the Centre during 48-96 hours after the moment of unprotected sexual contact. Nineteen women (54.3%) had the 1st phase of menstrual cycle, 16 (45.7%) had the 2nd phase. To exclude contraindication for hormonal contraception we conducted examinations (clinical, ultrasound, test for pregnancy). One dose of Escapelle containing 1,5 mg of levonorgestrel  was indicated  to all patients.


Results: Efficacy of Escapelle made up 97.2%. Pregnancy occurred in one case (2.8%) that was associated with the time period of more than 96 hours since the intercourse.  In  the 1st group 11 (58%) out of 19 women were noted to have menstruation delay, 5 had profound menstruations (26.3%). In the 2nd group five women (31.2%) had menstruation delay for 3-5 days, shortening of the cycle was found in four )25%) women, profound menstruations were in two (12.5%). Side effects were registered in six women (17.1%). Out of them sickness was noted in four (11.4%), vomiting in one (2.8%), tension of mammary glands were found in one case (2.8%).


Conclusion:  Escapelle is a highly efficient and tolerant method of emergency contraception. Taking into account the fact that side effects in the form of menstrual cycle disorders were found more often in women using Escapelle during the 2nd phase of it is necessary to recommend planned hormonal contraception. Efficacy decreases with the time period since the unprotected intercourse.

 


Objectives: to assess efficacy and tolerance of levonorgestrel-containing contraceptive Escapelle in women for emergency contraception


Materials and Methods: We investigated 35 women, aged from 18 to 39 (mean age 23.4+/-1.1) coming to the Centre for emergency contraception. All women visited the Centre during 48-96 hours after the moment of unprotected sexual contact. Nineteen women (54.3%) had the 1st phase of menstrual cycle, 16 (45.7%) had the 2nd phase. To exclude contraindication for hormonal contraception we conducted examinations (clinical, ultrasound, test for pregnancy). One dose of Escapelle containing 1,5 mg of levonorgestrel  was indicated  to all patients.


Results: Efficacy of Escapelle made up 97.2%. Pregnancy occurred in one case (2.8%) that was associated with the time period of more than 96 hours since the intercourse.  In  the 1st group 11 (58%) out of 19 women were noted to have menstruation delay, 5 had profound menstruations (26.3%). In the 2nd group five women (31.2%) had menstruation delay for 3-5 days, shortening of the cycle was found in four )25%) women, profound menstruations were in two (12.5%). Side effects were registered in six women (17.1%). Out of them sickness was noted in four (11.4%), vomiting in one (2.8%), tension of mammary glands were found in one case (2.8%).


Conclusion:  Escapelle is a highly efficient and tolerant method of emergency contraception. Taking into account the fact that side effects in the form of menstrual cycle disorders were found more often in women using Escapelle during the 2nd phase of it is necessary to recommend planned hormonal contraception. Efficacy decreases with the time period since the unprotected intercourse.

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