The use of contraceptive vaginal ring compared to oral contraceptive pill containing two active ingredients, estradiol valerate and dienogest, in two groups of adolescents. Preliminary report
ESC Congress Library. Tsikouras P. May 4, 2016; 126904; A-078 Disclosure(s): NO CONFLICT OF INTEREST
Dr. Panagiotis Tsikouras
Dr. Panagiotis Tsikouras
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Objectives: The use of effective birth-control methods in regular basis is the primary strategy for preventing unintended pregnancies. In teenagers, the lack of orientation and the premature sexual activity are the main reasons of unintended pregnancies. Teenagers are insufficiently informed about contraception by their parents, at school, or through public media. The purpose of this study was to compare the efficacy and acceptability of two contraception methods.

Method: Data was collected from the family planning centre in the Department of Obstetrics and Gynaecology of Democritus University of Thrace during the period from 1 January 2010 to 31 December 2014.The study included 85 teenage participants,aged 13-19 years,55 Christian Orthodox (Group A) and 30 Muslims (Group B) living in Thrace. All participants had signed a written consent. None of them had contraindications in the use of oral contraceptives (OCs). In subgroup Aa, including 35 teenagers, combined Oral contraceptive pills contained estrdiol valerate and dienogest was administrated, while in the participants of subgroup Ab, including 20 participants,  NuvaRing was used in accordance to the instructions of the product information. In Group B the use of OCs and Nuvaring was 20 subgroup Ba and 10 teenagers subgroup Bb respectively All teenagers completed questionnaire regarding adverse events .Statistical analysis was performed using one way analysis of variance (ANOVA), followed by Turkey’s test, chi-square test and multiple logistic regression analysis.

Results: The participants were observed for 24 consecutive cycles. There were no significant differences in demographic characteristics between two groups. The number of the participants in the both Nuvaring subgroups declined to 18,15,10 in subgroup Ab and 8,7,6 in subgroup Bb at 2,5,8 months respectively. The reasons were adverse effects .like vomiting,nausea,headache decreased libido,vaginitis. In one case in the subgroup Ab and in two cases in the subgroup Bb pregnancy was reported. Adverse effects and unintended pregnancies in the subgrups of OC Aa and Ba were not mentioned .The participants in the OC subgroups did not notice any adverse effects except mid menstrual bleeding and emotional instability because of  the  daily Pill administration.

Conclusions: Although the study sampling is small, the nuvaring is a good alternative to a OC in teenagers,but more prospective studies are necessary to confirm the effectiveness of the nuvaring in this populstion. Information about contraceptive use in teenagers can be used to guide the development of state programs regarding unwanted pregnancies.

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