PROFILACTIC VACCINATION IN CERVICAL CANCER
ESC Congress Library. Crauciuc E. 05/10/18; 208132; ESC186
Assoc. Prof. Eduard Crauciuc
Assoc. Prof. Eduard Crauciuc
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Abstract
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Objective(s): Every year, about 500.000 women worldwide get sick and almost half of them die because of cervical cancer. For Europe, the statistical data show that every year almost 60.000 women get this type of cancer. In Romania, HPV infection is generally associated with cervical cancer. Still, HPV also causes other oncologic and dermato-venereal disorders (venereal vegetation), which amplifies the dimension of this public health issue. 90% of the venereal vegetation is caused by HPV infection (types 6, 11) and can be prevented by the tetravalent anti-HPV vaccine. Over 80% of the adult people are exposed to HPV; morbidity can be diminished with over 70% through vaccination. It is very important for the family planning offices to perform screening and treatment of pre-invasive cervical lesions, and to collaborate with the specialized physicians in the specialized medical units. Although the family planning offices have limitations regarding the services offered, they cannot ignore the possibility of diagnosing and registration for the patients with risk, with the purpose of treating and monitoring them. Design and methods: Based on the cases studied and following the screening performed, in the context of drawing the profile for the patient that is susceptible of developing a pre-invasive lesion of the cervix, the specialized doctors in collaboration with the general practitioners and the family planning physicians convinced 125 of the 2,439 patients studied from a private practice in Iaşi-Romania (5.1%) to get vaccinated and 100 from the 7,000 patients studied in the Hospital from Buzău-Romania (7%). Results: The most commonly used vaccine was Silgard (60.9%). When considering age, we noticed a significantly higher number of patients getting the vaccine under 20 years old in Buzău when compared to Iași (84% vs 55.2%). The number of vaccinated patients coming from the city was significantly higher in Iaşi than in Buzău (72% vs 49%). The number of married patients who got vaccinated was significantly higher in Iaşi (76.7% vs 58%). The approach of pre-invasive lesions of the cervix is established from the moment an abnormal cytology is detected. About 60% of the women who were questioned have a high degree of cervical cytology affection, without recording significant differences between the age groups or where they come from. Conclusions: There were 15% major lesions in the investigated group, identified colposcopically during the first post-vaccination evaluation; for the next stages there no major lesions identified.
Objective(s): Every year, about 500.000 women worldwide get sick and almost half of them die because of cervical cancer. For Europe, the statistical data show that every year almost 60.000 women get this type of cancer. In Romania, HPV infection is generally associated with cervical cancer. Still, HPV also causes other oncologic and dermato-venereal disorders (venereal vegetation), which amplifies the dimension of this public health issue. 90% of the venereal vegetation is caused by HPV infection (types 6, 11) and can be prevented by the tetravalent anti-HPV vaccine. Over 80% of the adult people are exposed to HPV; morbidity can be diminished with over 70% through vaccination. It is very important for the family planning offices to perform screening and treatment of pre-invasive cervical lesions, and to collaborate with the specialized physicians in the specialized medical units. Although the family planning offices have limitations regarding the services offered, they cannot ignore the possibility of diagnosing and registration for the patients with risk, with the purpose of treating and monitoring them. Design and methods: Based on the cases studied and following the screening performed, in the context of drawing the profile for the patient that is susceptible of developing a pre-invasive lesion of the cervix, the specialized doctors in collaboration with the general practitioners and the family planning physicians convinced 125 of the 2,439 patients studied from a private practice in Iaşi-Romania (5.1%) to get vaccinated and 100 from the 7,000 patients studied in the Hospital from Buzău-Romania (7%). Results: The most commonly used vaccine was Silgard (60.9%). When considering age, we noticed a significantly higher number of patients getting the vaccine under 20 years old in Buzău when compared to Iași (84% vs 55.2%). The number of vaccinated patients coming from the city was significantly higher in Iaşi than in Buzău (72% vs 49%). The number of married patients who got vaccinated was significantly higher in Iaşi (76.7% vs 58%). The approach of pre-invasive lesions of the cervix is established from the moment an abnormal cytology is detected. About 60% of the women who were questioned have a high degree of cervical cytology affection, without recording significant differences between the age groups or where they come from. Conclusions: There were 15% major lesions in the investigated group, identified colposcopically during the first post-vaccination evaluation; for the next stages there no major lesions identified.
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