EMERGENCY CONTRACEPTION AND THROMBOSIS - A REVIEW
ESC Congress Library. monica pereira m. 05/10/18; 208182; ESC285
Prof. maria monica pereira
Prof. maria monica pereira
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Abstract
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INTRODUCTION: Emergency contraception consists of concentrated hormonal compounds used for a short time period which, if taken after unprotected intercourse, may prevent pregnancy. In this context, as there are low evidences of long-term side effects it is believed that as well as in continuous contraception there may be a greater risk of cardiovascular disease and thromboembolic events. This study aims to analyze if there is an association between the use of emergency contraceptives and thromboembolic events. DESING AND METHODS: Literature review of the last five years through Pubmed and Scielo databases with the descriptors "emergency contraception", "same-day contraception" and "thrombosis". RESULTS: A shortage of studies on emergency contraception has been observed, which may be attributed to the difficulty in identifying these patients, since these methods are sporadic and do not require prescription. The main reported side effects were systemic and without clinical significance, such as nausea, headache, edema and delayed menstrual period. In relation to the increased risk or prevalence of cardiovascular diseases and thromboembolic events, no evidence was found. Although the hormonal dosage found in these drugs resembles the full dosage of long-term use of oral contraceptives, no study has been able to demonstrate that its effects on blood circulation and coagulation are comparable to those of continuous use. In addition, most of the studies did not present significant samples and tools for the evaluation of the risk of rare events. CONCLUSION: Emergency contraception methods are still poorly studied, somewhat on the acount of the difficulty of monitoring users and also because of the scarcity of resources for assessing the risks of this sporadic drugs. In general, it is observed that the major problems are related to the immediate and mild systemic side effects. The association with the risks demonstrated in the continuous use of hormonal contraception, such as cardiovascular and thromboembolic events, was not observed in any of the current classes of emergency contraception.
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